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Old 03-03-2007, 11:38 PM
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MSM: revisited

Hi all,

it seems some of you have a found a treatment that has worked to get rid of your old KP ... but when you stop, it comes back.

Just wondering if any of you has considered supplementing your diet with MSM to prevent new KP to resurface.


Q: How does MSM work?

A:The exact mechanisms of how MSM works are still being identified in ongoing scientific research. However, scientific studies have now confirmed that MSM is a safe and effective anti-inflammatory agent. It may also contribute to the integrity of joint cartilage and other connective tissue.
In recent animal research conducted in Japan, MSM was found to act as an immunomodulator, preventing the immune system from mounting dangerous autoimmune responses to noxious stimuli. See study . It also prevented local inflammation to a significant enough degree as to halt an autoimmune reaction at the genetic stage of induction. It appears to affect autoimmune responses, such as the immune system's development of antibodies against its own tissues.
MSM has been shown to inhibit the development of abnormal antibodies to collagen, and to prevent production of rheumatoid factor and antinuclear antibodies (ANA).
Though the pain relieving properties of MSM are well known, mechanisms by which it accomplishes this are still under investigation. MSM most likely inhibits inflammatory prostaglandins and leukotrienes, hormone-like substances that create inflammatory cascades in the body associated with pain production.
MSM's effects on connective tissue are also well known. It is presumed, though not proven, that the beneficial clinical effects noted in humans on skin, hair, nails, and joint cartilage (as well as on hooves and coats in animals) has to do with MSM's sulfur content. Sulfur is abundant in connective tissue, and sulfur depletion in connective tissue is known to lead to problems. Because MSM is 34% sulfur, it is likely that the integrity of connective tissue is enhanced with MSM supplementation.
MSM's benefits are those of a dietary supplement. It should not be used to treat serious diseases unless under the supervision of a medical doctor.

http://arthritis.about.com/gi/dynami...facts/faq.html
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Old 03-04-2007, 01:17 PM
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I started supplementing with MSM 2 days ago. I eat 2 grams a day but I´m not sure how much I´m supposed to eat... I have e-mailed the retailer and I´m now waiting for their answere. Hopefully MSM at least will help a little bit...Anyone out there that have doseage-suggestions and that have had good results with MSM??
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Old 03-04-2007, 01:50 PM
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If you click on the link I posted, you'll find the following with respect to dosage:

Q: How much MSM can I take? Are there any side effects?

A: Clinical trials have investigated doses ranging from 1,500 mg per day up to 6,000 mg per day. Stanley Jacob, MD reports using MSM in his patients at doses of up to 100 grams per day with no ill effects under highly controlled medical treatment regimens in a hospital clinic (MSM: The Definitive Guide). MSM toxicity studies indicate that these large doses do not present safety issues, however it is possible that they could result in occasional loose stools or other minor effects.
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